RIGONOMA GAUZE

Description
Rigenoma Gauze protects damaged skin while stimulating regeneration.
Ozoile combined with hyaluronic acid, aloe vera, and stonecrop to optimize hydration and enhance tissue regeneration. Blackcurrant, with cortisone-like effects, glycyrrhetic acid, butcher's broom, and calendula, enhance the anti-inflammatory effect. Alpha-lipoic acid helps prevent and repair oxidative damage.
It releases immediately available ^O2 , which activates slowed mitochondrial metabolism, providing immediate energy to cells. It reduces oxygen consumption associated with inflammation, infection, and degenerative processes. It reactivates microcirculation by stimulating the transcription of VEGF, a growth factor for angiogenesis.
It inactivates cyclo-lipo-oxygenase (COX ₂ ) reducing the prostaglandins responsible for pain and edema and activates aminoxidases (MAO and DAO) which degrade histamine and serotonin which cause redness and itching.
It has bactericidal, fungicidal, and virustatic action: oxidation of the bacterial and fungal capsule wall; inhibition of receptors present on the viral surface; lengthening of relapse times by stimulating the immune defenses.
It stimulates the synthesis of fibroblasts, collagen, and new blood vessels by acting on the growth factors FGF, PDGF, EGF, VEGF, and HIF-1-alpha. It promotes cell adhesion in the formation of new tissue by stimulating the transcription of e-cadherins.

How to use
Apply one or more gauze pads depending on the size of the area to be treated, covering the entire area with sterile gauze or a suitable bandage. Repeat the dressing twice daily or as directed by your doctor. The product can also be used under an occlusive dressing.

Warnings
If you are being treated with hypoglycemic drugs, consult your doctor before using the product.

Conservation
Shelf life in intact packaging: 48 months.

Format
Pack of 10 sachets.
Gauze size: 10x10 cm.

Cod. 0613

Bibliography
I. Zanardi, S. Burgassi, E. Paccagnini, M. Gentile, V. Bocci, and V. Travagli. What Is the Best Strategy for Enhancing the Effects of Topically Applied Ozonated Oils in Cutaneous Infections? Biomed Res Int. 2013 Oct 27.
Nathália R. de Almeida, Adilson Beatriz, Ana Camila Micheletti and Eduardo J. De Arruda, Ozonized vegetable oils and therapeutic properties: A review. Orbital, The Electronic Journal Of Chemistry, Volume 4, Number 4, October-December 2012.
Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM, Therapeutic effects of topical application of ozone on acute cutaneous wound healing. J Korean Med Sci, 12 June 2009.
N. Geweely. Antifungal Activity of ozonized olive oil. Int. J. Agri. Boil., Vol.8, No. 5, 2006 Koichi Tamoto, Akironi Yamazaki, Hiromi Nochi, Toshiaki Miura. Ozonides of olive oil methyl oleate inhibited the expression of cyclooxygenase -2 through the suppression of IkB/NFkB-dependent pathway in lipopolysaccharide-stimulated macrophage-like THP-1 cells. IOA17th World Ozone Congress- Strasbourg 2005.
LA Sechi, I. Lezcano, N. Nunez, M. Espim, I. Duprè, A. Pinna, P. Molicotti, G. Fadda and S. Zanetti. Antibacterial activity of ozonized sun ower oil. Journal of Applied Microbiology 2001, 90, 279±284.
Matsumoto, Akiyo; Shotaro Sakurai; Nariko Shinriki; Shigeru Suzuki & Toshiaki Miura, Therapeutic Effects of Ozonized Olive Oil in the Treatment of Intractable Fistula and Wound after Surgical Operation. Japan, J. Clin. Surg., 61(6) 7-13 (2000).