Trimbow is a breathing aid medicine that contains three active substances:
- beclomethasone dipropionate,
- formoterol fumarate dihydrate and
- glycopyrronium.
Beclomethasone dipropionate belongs to a group of medicines called corticosteroids, which work to reduce swelling and irritation in your lungs.
Formoterol and glycopyrronium are medications called long-acting bronchodilators.
They work in different ways to relax the muscles in your airways, helping to open your airways more and allowing you to breathe more easily.
Regular treatment with these three active substances helps to improve and prevent symptoms such as shortness of breath, wheezing and coughing in adult patients with obstructive pulmonary disease.
Trimbow is used for the regular treatment of
- chronic obstructive pulmonary disease (COPD) in adults
- bronchial asthma in adults.
Trimbow can reduce exacerbations (worsening) of COPD and asthma symptoms.
COPD is a serious, long-term disease in which the airways become blocked and the air sacs inside the lungs become damaged, leading to difficulty breathing.
Asthma is a serious, long-term disease in which the muscles surrounding the airways tighten (bronchoconstriction), swell, and become irritated (inflammation). Symptoms come and go and include shortness of breath, wheezing, chest tightness, and coughing.
You should use Trimbow every day, not just when you have breathing problems or other asthma symptoms. This will ensure that your asthma is adequately controlled. Do not use this medicine to relieve a sudden attack of shortness of breath or wheezing.

Do not use Trimbow:
- if you are allergic to beclomethasone dipropionate, formoterol fumarate dihydrate and/or glycopyrronium or any of the other ingredients of this medicine.

Talk to your doctor or pharmacist before taking Trimbow.

Pregnancy and breastfeeding:
If you are pregnant or breast-feeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before using this medicine.
You should only use Trimbow during pregnancy if your doctor tells you to do so. It is preferable to avoid using Trimbow during labour due to the inhibitory effects of formoterol on uterine contractions.
You should not use Trimbow during breast-feeding. You and your doctor should decide whether to discontinue breast-feeding or to discontinue/abstain from Trimbow treatment.
Trimbow, taking into account the benefit of breast-feeding for your child and the benefit of the treatment for you.

Driving and using machines:
Trimbow is unlikely to affect your ability to drive or use machines.

Always use this medicine exactly as your doctor or pharmacist has told you. Talk to your doctor or pharmacist if you are not sure.

The recommended dose is two puffs in the morning and two puffs in the evening.
Do not use more than your doctor tells you to use.
You should use Trimbow every day, even when your asthma is not bothering you.
Do not use this medicine to relieve a sudden attack of shortness of breath or wheezing.

If you think this medicine is not very effective, talk to your doctor.
If you have previously used a different inhaler containing beclomethasone dipropionate, ask your doctor for advice, as the effective dose of beclomethasone dipropionate in Trimbow for the treatment of obstructive pulmonary disease may be lower than that in other inhalers.

Route of administration:
Trimbow is intended for inhalation use.
You need to inhale the medicine through your mouth, and this takes the medicine directly to your lungs.
This medicine is contained in a pressurized bottle, in a plastic inhaler with a mouthpiece applicator.

If you have any further questions on this medicine, ask your doctor or pharmacist.

- The active substances are: beclomethasone dipropionate, formoterol fumarate dihydrate and glycopyrronium.
Each delivered dose (the dose delivered by the buccal applicator) contains 88 micrograms of beclomethasone dipropionate, 5 micrograms of formoterol fumarate dihydrate and 9 micrograms of glycopyrronium (as 11 micrograms of glycopyrronium bromide).
Each metered dose contains 100 micrograms of beclomethasone dipropionate, 6 micrograms of formoterol fumarate dihydrate and 10 micrograms of glycopyrronium (as 12.5 micrograms of glycopyrronium bromide).
- The other ingredients are: lactose monohydrate (see section 2) and magnesium stearate.

Warning:
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

1 bottle