Axtrifia contains the active substance cefixime. It belongs to a group of antibiotics called cephalosporins, used to treat infections caused by bacteria in adults and adolescents aged ≥ 12 years, such as:
• Acute ear infection
• Acute infection of the nasal cavity and sinuses
• Acute exacerbation of chronic bronchitis
• Community-acquired pneumonia
• Uncomplicated urinary tract infections
• Acute uncomplicated gonorrhea
You should talk to a doctor if you do not feel better or if you feel worse.

Do not take Axtrifia 200 mg if:
• you are allergic to cefixime or any of the other ingredients of this medicine.

Talk to your doctor or pharmacist before taking Axtrifia.

Pregnancy, lactation and fertility:
If you are pregnant or breast-feeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
Task:
Axtrifia 200 mg should be used during pregnancy only on the advice of your doctor.
If you discover that you are pregnant during treatment, contact your doctor, who is the only person who can decide whether you should continue.
Breastfeeding:
You should not take this medicine while breastfeeding unless clearly indicated by your doctor.
However, if your child develops digestive problems (diarrhoea, infection with a fungus called Candida) or pimples, stop breast-feeding or taking the medicine and contact your doctor immediately. Your doctor will decide whether you should stop breast-feeding or stop/abstain from treatment with Axtrifia 200 mg, taking into account the benefit of breast-feeding for your child and the benefit of treatment for you.

Driving and using machines:
Cefixime may cause dizziness. If affected, you should not drive or use machines.

Axtrifia 200 mg contains sodium:
This medicine contains less than 1 mmol sodium (23 mg) per film-coated tablet, that is to say essentially “sodium-free”.

Always take this medicine exactly as your doctor or pharmacist has told you.
Talk to your doctor or pharmacist if you are not sure.
Dosage:
Your doctor will decide the correct dose of Axtrifia 200 mg and tell you how long to take the medicine. The number of Axtrifia 200 mg tablets you should take will depend on your condition. Follow your doctor's instructions exactly and never change the dose. Ask your doctor or pharmacist if you are not sure.
how much medicine to take or when to administer it.
Adults and adolescents (≥ 12 years):
The recommended daily dose is 400 mg orally:
1 x 400 mg per day

If your doctor has prescribed one dose per day, it should be taken every 24 hours. If your doctor has prescribed two doses per day, each dose should be taken every 12 hours.
The medicine should always be taken at the same time of day.

Duration of treatment:
Most infections can be treated within 7 days of treatment. However, in severe cases, Axtrifia 200 mg may be used for 14 days.

Children under 12 years of age:
Please note that Axtrifia 200 mg tablets are not suitable for children, oral suspension can be used instead or you should contact your doctor for more information.

Elderly:
For the elderly, the doses are the same as for adults, provided that kidney function is normal.

Kidney problems:
If you have severe kidney problems or are on dialysis, your doctor will reduce your dose.
There are insufficient data on the use of Axtrifia 200 mg in children with kidney problems. Therefore, Axtrifia is not recommended for use in these patients. In case of creatinine clearance values ​​< 20 ml/min, in ambulatory peritoneal dialysis or hemodialysis, the recommended dose is 200 mg once daily.

Impaired liver function:
No dose adjustment is necessary in patients with hepatic impairment.

Method of administration
For oral administration.
The tablet should be taken with a sufficient amount of water and the tablets should be swallowed whole.
Axtrifia 200 mg can be taken with or without food.

If you have any further questions on this medicine, ask your doctor or pharmacist.

- The active substance is cefixime.
Each film-coated tablet contains 200 mg cefixime (as cefixime trihydrate).
- The other components are:
- in the tablet core: calcium hydrogen phosphate, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, magnesium stearate.
- in the tablet film: macrogol - polyvinyl alcohol copolymer, talc, mono/diglycerides, titanium dioxide (E 171), polyvinyl alcohol.

Warning:
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

10 film-coated tablets