UTI Free

UTI Free is available in the form of sachets of soluble powder, containing the following composition per sachet:

• L-methionine – 1.5 g
• L-ascorbic acid (vitamin C) – 1 g
• D-mannose – 1.5 g
• Calcium citrate – 15 mEq
• Sweetener: sucralose

UTI Free is indicated as an adjunct in the management of lower urinary tract infections (UTIs), especially recurrent ones. Due to its composition, the product has the following effects:

• Promotes the elimination of uropathogenic bacteria by inhibiting their adhesion to the urothelial epithelium (through D-mannose);
• Acidifies urine, preventing the proliferation of bacteria (through L-methionine and vitamin C);
• Supports normal urinary function, helping to maintain a biological environment unfavorable to the formation of bacterial biofilm;
• Can be used as support in the post-infectious period or in a prophylactic context.

The dosage of this product is one sachet in the morning and one in the evening for 7 days. The evening dose is particularly important because nitrite levels and urine acidity reach their highest levels during sleep.

For long-term use, it is recommended to take one sachet of UTI Free every evening, dissolved in a glass of water, milk, or fruit juice, with or without food.

The duration of administration may vary depending on individual needs and the recommendation of a doctor or pharmacist, with the possibility of extending the treatment in the long term in cases of recurrent infections.

The use of UTI Free is contraindicated in the following situations:

• hypersensitivity to any of the product's components (e.g., L-methionine, ascorbic acid, D-mannose, calcium citrate)
• severe liver or kidney failure
• untreated metabolic acidosis or hypercalcemia

If you suffer from severe chronic diseases, it is advisable to consult your doctor before taking this product.

UTI Free can be taken by adults, including the elderly and patients with diabetes mellitus.

The product is well tolerated and compatible with restrictive diets. It does not contain lactose or gluten, and the sucralose used as a sweetener does not affect blood sugar levels.

It is important to stay well hydrated while using the supplement to facilitate the elimination of bacteria and support the effectiveness of the active ingredients.

UTI Free is generally well tolerated. However, in rare cases, the following may occur:

• mild gastrointestinal disorders (nausea, abdominal discomfort, flatulence);
• mild allergic reactions (skin rash, itching) – extremely rare.

If unusual or severe reactions occur, discontinue use and consult a doctor.

L-methionine in UTI Free may influence the metabolism of some drugs by altering the urinary pH, thus affecting the elimination of acidic or basic compounds.

D-mannose does not interact significantly with other drugs, as it is rapidly absorbed and eliminated in the urine.

No cases of severe overdose with UTI Free have been reported. However, taking doses much higher than those recommended could lead to excessive urinary hyperacidity, stomach discomfort, or diarrhea (due to vitamin C or sucralose), and risk of kidney stones at very high doses of vitamin C or calcium.

In case of overdose, it is recommended to discontinue administration and institute general symptomatic measures.

UTI Free should be stored at room temperature (15–25°C), in a place away from moisture and direct light. Keep out of the reach and sight of small children. Do not use after the expiry date indicated on the package.

• PubMed, Prevention of reinfection with L-methionine in patients with recurrent urinary tract infection
• PubMed, Why D-mannose may be as effective as antibiotics in the treatment of acute uncomplicated lower urinary tract infections - Preliminary considerations and conclusions from a non-interventional study
• WebMD, D-mannose
• BMC Microbiology, Antibacterial effect of vitamin C against uropathogenic E. coli in vitro and in vivo