Flexitol

Flexitol is available as a heel or hand balm in a 56 g bottle, adapted to various skin needs:

• Flexitol Heel Balm 25% Urea – heel balm for the rapid treatment of very dry and cracked skin
• Flexitol Hard Skin and Callus Balm 22% Urea – exfoliating balm for thickened skin and calluses, with visible results in 3 days
• Flexitol Hand Balm 10% Urea – balm that works effectively on cracked hands, dry, rough, irritated, or itchy skin and fingers.

Flexitol is indicated for:

• treating very dry, rough, and dehydrated skin on the hands, feet, and heels;
• relieving and preventing painful cracks on the heels;
• improving the appearance and texture of the skin in people with anhidrosis or xeroderma;
• reducing calluses and thickened skin;
• skin care in patients with diabetes mellitus, where excessive dryness can predispose to complications;
• maintaining skin hydration after skin repair to prevent recurrence.

Flexitol heel cream or Flexitol hand balm should be used according to the manufacturer's recommendations and, if necessary, as directed by a doctor.

It is recommended to apply twice a day, in the morning and in the evening, to ensure optimal effect. After healing, the product can be used once a day to maintain hydration and prevent dryness from recurring. 

Flexitol is intended for external use only and should not be applied to broken or infected skin.

Flexitol skin balm is contraindicated in the following situations:

• known hypersensitivity to urea or any of the product's excipients;
• application on open wounds, ulcers, or damaged skin;
• use in young children, unless recommended by a pediatrician.

To apply Flexitol heel balm, wash and dry your feet before use, then gently massage the product into the affected areas. 

The product should not be applied to mucous membranes or near the eyes. In case of local irritation, treatment should be discontinued and a doctor consulted.

During pregnancy and breastfeeding, local use is considered safe, but it is recommended to apply to small areas and avoid contact with the nipple area.

Reported side effects are rare and usually minor:

• local hypersensitivity reactions (itching, erythema, burning sensation);
• irritation when applied to very sensitive skin;
• in isolated cases, contact dermatitis.

Most reactions are transient and disappear once use is discontinued.

Flexitol acts locally and therefore does not interact with systemic drugs. 

The risk of interactions is minimal, but simultaneous application with other irritating topical creams (e.g., products with high concentrations of salicylic acid or retinoids) should be avoided.

Since Flexitol is a product for external use, the risk of overdose is very low. However, accidental ingestion may cause digestive disorders (nausea, vomiting, diarrhea), in which case immediate medical attention is required. Excessive application to the skin does not usually lead to toxic effects, but may cause local irritation.

Flexitol should be stored at room temperature (below 25°C), away from heat sources and direct sunlight. Do not freeze. Keep out of reach of children. Once the tube has been opened, the product should be used within the expiry date indicated on the packaging.

• PubMed, Urea in dermatology: a review of its emollient, moisturizing, keratolytic, skin barrier strengthening, and antimicrobial properties
• ScienceDirect, The influence of creams with different urea concentrations on plantar skin hydration
• Wiley Online Library, The history of urea as a dermatological agent in clinical practice
• Wolters Kluwer, The effect of topical urea treatment on ichthyosis, atopic dermatitis, psoriasis, and other skin conditions — a systematic review