PRODUCT NAME
CANIHELMIN PLUS

50 mg/144 mg/150 mg tablets for dogs.

NAME OF THE VETERINARY MEDICINAL PRODUCT
Canihelmin plus 50 mg/144 mg/150 mg tablets for dogs.
Praziquantel, pyrantel embonate, febantel.

DECLARATION OF ACTIVE SUBSTANCES AND OTHER INGREDIENTS
Each tablet contains:

Active substances:
Praziquantel 50 mg;
Pyrantel embonate 144 mg (equivalent to 50 mg pyrantel);
Febantel 150 mg.

The tablet is yellowish, round, flat, with a cross-shaped indentation on one side.
The tablet can be divided into quarters.

Directions
Treatment of combined infections with nematodes and cestodes belonging to the following species:

Nematodes:
Roundworms: Toxocara canis, Toxascaris leonina (adults).
Hookworms: Uncinaria stenocephala, Ancylostoma caninum (adults).
Ringworm: Trichuris vulpis (adults).

Cestodes:
Roundworms: Echinococcus spp. (Echinococcus granulosus, Echinococcus multilocularis), Taenia spp. (Taenia hydatigena, Taenia pisiformis, Taenia taeniaeformis), Dipylidium caninum (adults).

CONTRAINDICATIONS
Do not use simultaneously with piperazine compounds.
Do not use in case of hypersensitivity to the active substances or to any of the excipients.

ADVERSE REACTIONS
In very rare cases, gastrointestinal disturbances (diarrhoea, vomiting) have been observed. If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinary surgeon.
The frequency of adverse reactions is defined using the following convention:
- Very common (more than 1 in 10 animals showing adverse reactions during a treatment);
- Common (more than 1 but less than 10 animals in 100 animals);
- Uncommon (more than 1 but less than 10 animals in 1,000 animals);
- Rare (more than 1 but less than 10 animals in 10,000 animals);
- Very rare (less than 1 animal in 10,000 animals, including isolated reports).

TARGET SPECIES
Dogs.

DOSAGE FOR EACH SPECIES, ROUTE(S) OF ADMINISTRATION AND METHOD OF ADMINISTRATION
Oral administration.
The recommended doses are: 1 tablet per 10 kg body weight as a single dose (5 mg praziquantel, 15 mg febantel and 14.4 mg pyrantel embonate, per kg body weight). To ensure correct dosing, body weight should be determined as accurately as possible.

Puppies and small dogs
3-5 kg ​​body weight 1/2 tablet;
> 5-10 kg body weight 1 tablet.

Medium-sized dogs
> 10-20 kg body weight 2 tablets;
> 20-30 kg body weight 3 tablets.

Large dogs
> 30-40 kg body weight 4 tablets.

If there is a risk of reinfestation, the veterinarian's advice on the need and frequency of repeated administration should be sought.

RECOMMENDATIONS ON CORRECT ADMINISTRATION
This product can be administered directly to the dog or incorporated into the food (in a piece of meat, cheese, etc.). It is recommended to treat animals before feeding and it is not necessary to withhold food before or after treatment.

WAITING TIME
That's not the case.

SPECIAL STORAGE PRECAUTIONS
Keep out of sight and reach of children.
This veterinary medicinal product does not require any special storage conditions.
Do not use this veterinary medicinal product after the expiry date which is stated on the carton after EXP {month/year}.
The expiry date refers to the last day of that month.
Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Shelf life of divided tablets: use immediately.

SPECIAL WARNING(S)
Special warnings for each target species:
Fleas serve as intermediate hosts for a common type of flatworm - Dipylidium caninum. Flatworm infestations are sure to recur if intermediate hosts such as fleas, mice, etc. are not controlled.
Flatworm infestation is less likely in puppies younger than 6 weeks old.
Parasite resistance to any particular class of anthelmintics may develop as a result of frequent, repeated use of a particular class of anthelmintics.
Care should be taken to avoid the following practices as they increase the risk of developing resistance and may ultimately lead to ineffective treatment.
Strategies that should be avoided as they may lead to an increased risk of developing resistance to anthelmintic substances include:
- frequent and repeated use of anthelmintics from the same class over a long period of time;
- underdosing.

Clinical cases suspected of anthelmintic resistance should be further investigated using appropriate tests (e.g., faecal egg count reduction test). In cases where the results of the test(s) strongly suggest resistance to a particular anthelmintic, one belonging to a different pharmacological class and having a different mode of action should be used.

Special precautions for use in animals:
To ensure the correct dosage is administered, body weight should be determined as accurately as possible. Do not use in dogs less than 2 weeks of age and/or weighing less than 3 kg.
Any unused divided tablet should be discarded.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Avoid contact with eyes. In case of contact with eyes, rinse with plenty of water.
Avoid hand-eye and hand-mouth contact while handling the product.
In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
Wash your hands after use.

Gestation:
Teratogenic effects attributed to high doses of febantel have been reported in sheep and rats. Studies in early pregnancy have not been conducted in dogs. Use of the product during pregnancy should be based on a benefit-risk assessment by the responsible veterinarian.
Bitches should not be treated during the first 40 days of gestation.
Do not exceed the recommended dose when treating pregnant bitches.
Interactions with other medicinal products or other forms of interaction:
Concomitant use with other cholinergic compounds may lead to toxicity.
This product should not be administered concomitantly with other substances with cholinergic effects.
Simultaneous administration of compounds that inhibit acetylcholinesterase - AChE activity (e.g., organophosphates) may increase the systemic effect of pyrantel.
Do not use simultaneously with piperazine compounds as the anthelmintic effects of pyrantel and piperazine may be antagonized.

Overdose (symptoms, emergency procedures, antidote):
The combination of praziquantel, pyrantel embonate and febantel is well tolerated in dogs. In safety studies, a single dose of 5 times the recommended dose or more occasionally caused vomiting.

Incompatibilities:
That's not the case.

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS, IF ANY
Medicines should not be thrown away in wastewater or household waste.
Ask your veterinarian for information on how to dispose of medicines no longer required. These measures help protect the environment.

OTHER INFORMATION
For animal use only. To be supplied only on veterinary prescription.

Packaging presentation:
2 x 10 tablets or 10 x 10 tablets.

Currently, product safety information is not available.

Currently, manufacturer information is not available.

Currently, information about the person responsible is not available.

Size: Small, Medium, Large

Age: Adult, Senior

Presentation type: Tablets

Action: Internal deworming

Pieces Set: 10 pieces

Brand Name: Dechra

Quantity: 10 pcs