ISDIN Ureadin Ultra 20 Anti-Roughness Cream: Intensive care for very dry, rough and thickened skin

Very dry, rough, and brittle skin, often accompanied by flaking and itching, presents a common dermatological challenge. These skin conditions can indicate hyperkeratosis – a thickening of the outer layer of skin as a protective reaction of the body. ISDIN Ureadin Ultra 20 Anti-Roughness Cream was specially developed to address these complex needs and sustainably improve skin texture.

Effective exfoliation and deep moisturizing care

At the heart of this effective formula is a high concentration of 20% urea . This natural moisturizing factor provides intense hydration and helps the skin restore its natural moisture balance. At the same time, urea in this concentration offers a gentle exfoliating effect, helping to remove dead skin cells and smooth calloused skin. The result is a significant reduction in flaking and noticeably smoother skin. This moisturizing body cream is ideal for dry and calloused skin.

Rich care and a strengthened skin barrier

This rich body cream is enriched with avocado oil , which intensely nourishes and cares for the skin, thus supporting skin regeneration. Regular use of Ureadin Ultra 20 strengthens the skin's barrier function, makes it more resilient, and helps prevent further moisture loss. Your skin becomes supple and feels pleasant again – without any greasy residue.

Clinically proven: Visible results and easy application

The effectiveness of ISDIN Ureadin Ultra 20 Anti-Roughness Cream is dermatologically tested and scientifically proven. One study showed a 35% reduction in the thickness of the stratum corneum in patients with hand dermatitis¹, demonstrating the restoration of healthy skin architecture.

Results after only 4 weeks of use²:

• 94% reduced rough and flaky patches.
• 97% felt more comfortable.
• 94% confirmed more elastic skin.

The urea cream absorbs quickly without leaving a greasy residue, making it particularly pleasant to use. It's the ideal cream for calloused feet, dry knees, rough elbows , and keratosis pilaris (chicken skin) . Discover the improvement after just 30 days of use and give your skin the intensive care it needs.

¹ Effective skin protection through the application of a 20% urea-based cream in patients with irritant or allergic skin dermatitis. Silvana Ciardo, Giovanna Mazzaglia, Andrea Meschieri, Maurizio Greco, Giovanni Pellacani. National AIDNID Congress Turin, March 12–14, 2015.
² Clinical study on the subjective evaluation of the efficacy of the anti-wrinkle cream Ureadin Ultra20 over 4 weeks in 30 subjects of both sexes (18-70 years). Data in the archive 2013.